Man City will clash with Chelsea in a Premier League fixture at the Etihad Stadium on Saturday afternoon.
But De Bruyne expects Thomas Tuchel’s side to give Man City a ‘big test’ during the match.
Speaking at his pre-match press conference on Friday, the Belgium international said: “It is exciting. I think you always want to play in the biggest games.
“We had so many battles over the years where we have won and they have won a couple of games in the Premier League and Champions League.
“You always want to be on top and that is what we want to do tomorrow.
“It is a big game. They have been playing really well lately. I saw the Liverpool game (2-2 Premier League draw) and a little bit of the first Tottenham game (2-0 Carabao Cup win), so they have been in a good rhythm.
“I expect them to give us a big test.”
The kick-off time for the game is 1.30 pm.